Dosage
Librax is available in a capsule formulation. Each dose contains 5 milligrams (mg) of chlordiazepoxide and 2.5 mg of clidinium. The daily dosage can vary by the condition being treated.
Possible Side Effects
Librax is known to cause considerable side effects, although some people are affected more than others. Common side effects include drowsiness, dizziness, constipation, nausea, blurred vision, and dry mouth. Many of these resolve over time as your body adjusts to the medication.
Librax may cause menstrual irregularities in some women. Librax may also increase or decrease the sex drive (libido). Let your healthcare provider know if such symptoms develop, especially if they are intolerable or you are planning a family.
Serious side effects of Librax can occur in some people, including mental changes (such as confusion and coordination problems) and difficulty in urination. Call your healthcare provider immediately if you experience any such symptoms.
Librax can be psychologically and physically habit-forming. Let your healthcare provider know if you have a history of alcohol or drug abuse. Under the supervision of a healthcare provider, Librax can be used safely over the long term as long as the recommended dose is never exceeded.
Interactions
Librax is known to interact with numerous medications, either increasing or decreasing the concentration of a drug in the bloodstream. This can either lead to a worsening of side effects or reduce the efficacy of a drug. Key interactions include:
Antacids Anti-arrhythmia drugs like Pronestyl (procainamide) Anticoagulants like Coumadin (warfarin) Antidepressants Antihistamines Lanoxin (digoxin) Nizoral (ketoconazole) Monoamine oxidase (MAO) inhibitors Prednisone Reglan (metoclopramide) Sedatives like Ambien (zolpidem) and Halcion (triazolam) Tagamet (cimetidine) Thiazide diuretics like Dyazide (triamterene)
Librax should be not be taken with alcohol, as their combined use can increase the sedative effect. This includes alcohol found in over-the-counter cough suppressants or cold remedies like Nyquil.
Contraindications
Librax is contraindicated for use in people with certain diseases and medical conditions. This means that the drug should not be used under any circumstance. These include:
Cardiovascular instabilityDrug abuse or dependenceGlaucomaHepatic function impairmentHiatal hernia with reflux esophagitis Hypersensitivity to chlordiazepoxide hydrochloride and/or clidinium bromide Hypertension Hyperthyroidism Intestinal atonyIntestinal obstruction Mental depression Myasthenia gravis Prostatic hypertrophyPsychoses Pulmonary diseaseRenal function impairment
Women in their child-bearing years should use contraception if prescribed Librax. The risk of fetal harm is greatest during the first trimester when fetal cells are still specializing.
It is unknown if the metabolites of Librax can be passed through breastmilk. With that said, Librax can suppress the production of breast milk in nursing mothers.
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